Diagnosis: Molluscum Contagiosum

Molluscum contagiosum is caused by a virus that is a member of the poxvirus family. The two viral subtypes, MCV I and MCV II have an identical clinical presentation. The lesions are 2- to 5-mm umbilicated papules that range from flesh-colored to pearl-colored.

MC is common in children, especially those with a history of atopic dermatitis. They may occur anywhere on the skin, and are transmitted from skin to skin contact. Coming in contact with an object that has touched infected skin, such as a towel, toy, doorknob, faucet handle, or clothing, may transmit the disease.

In adults, lesions may present in the genital region, abdomen, and inner thighs, and are often sexually transmitted. Large lesions may occur in immunocompromised patients and may be difficult to treat.

The diagnosis is often straightforward, but a differential of benign epidermal tumors, verrucae, condyloma acuminate or herpes simplex (in the genital area), and basal cell carcinoma may be considered. In immunocompromised patients, lesions may resemble cryptococcus or other infectious diseases. Histopathology will reveal intracytoplasmic inclusion bodies named molluscum bodies in keratinocytes.

Treatment options vary. Spontaneous resolution may occur over several months; inflammation is a good sign the lesions may be resolving. Curettage, liquid nitrogen, topical retinoids, keratolytics, cantharidin, and imiquimod have all been reported as successful treatments. In children with atopic dermatitis, moisturization and hydration of the affected skin around the lesions is often soothing.